Francis Chinegwundoh - Emerging Technologies
MBBS MS FRCS (Eng & Ed) FRCS(Urol) FEBU
TUNA (transurethral needle ablation of prostate)
This is a relatively new technique to the UK, which I am able to offer. It has been widely used on the Continent and the USA for years.
With age, most men's prostates grow larger, resulting in irritating problems associated with urination. Benign prostatic hyperplasia (BPH) is a common condition affecting the prostate. It is a non-cancerous enlargement of the prostate that restricts the flow of urine from the bladder. Millions of men worldwide are affected by BPH, but fewer than five percent are receiving treatment. Fifty percent of men older than 50 and 80 percent of men older than 80 have some symptoms of BPH. This condition is the most common non-cancerous form of cell growth in men. While there is no definitive cause of BPH, factors that contribute to the condition include aging, hormones and growth factors.
Though BPH is not life threatening, it can lead to a reduced quality of life, causing discomfort, inconvenience, sleep disruption and embarrassment. BPH was traditionally treated by a method called Transurethral Resection of the Prostate (TURP). This involves inserting a scope into the urethra and removing a section of the obstructing prostate tissue. It involves surgical risks but remains a "standard."
Medication is also available to help treat BPH. Some relax the neck of the bladder while others shrink the prostate. These medications are effective, but not as effective as surgery. Within the past decade, a number of minimally invasive techniques have been developed to treat BPH. Transurethral Needle Ablation (TUNA) is one such technique that has fewer side effects than other minimally invasive laser or microwave treatments. The side effect profile also compares favorably to TURP.
How is TUNA performed?
During TUNA, the interior of the prostate is treated with low levels of radiofrequency energy in a manner which causes prostatic tissue coagulation or destruction. In the hands of a properly trained urologic surgeon, the procedure is rather simple to perform. Operating time is usually approximately thirty minutes. The procedure can almost always be performed using only local anesthesia and intra-venous sedation and is performed as a day case. During the TUNA procedure, a special lighted scope is inserted that employs two tiny needles that penetrate the prostate without damaging the wall of the urethra. The urologist then directs the needles into position and releases a controlled burst of radiofrequency energy which heats the enlarged prostate tissue to about 195 degrees without affecting nearby nerves, muscles or membranes. The two needles are moved into several different locations and the treatment repeated which destroys enough prostatic tissue to "open the pipes" a bit.
Over a period of a few months, the prostate shrinks away from the middle hole and opens the passageway and the narrowing in the urethra is reduced. Some patients are sent home with a small urinary catheter which is removed two to three days later and they can resume normal activity almost immediately. Other men may be able to avoid a catheter all together.
The procedure received marketing clearance from the U.S. Food and Drug Administration in 1996 for the treatment of symptoms due to urinary outflow obstruction secondary to benign prostatic hyperplasia (BPH) in men older than 50. Since its introduction, more than 33,000 TUNA procedures have been performed worldwide.
TVT (tension-free tape)
Introduction
The urinary bladder stores urine which is coninuously excreted by the kidneys. When the bladder is full the sphincter muscles along the length of the urethra (the tube leading from the bladder) relax and the bladder contracts and empties. Once the bladder is empty, the bladder muscle relaxes and the urethral sphincter closes again.
Urinary incontinence affects up to 15% of women and increases with age. Incontinence occurs when the sphincter muscle does not close properly or the bladder contracts when it should not. Inadequate closure of the sphincter may follow damage to the muscles and nerves of the pelvic floor after vaginal delivery. This may be aggravated by the menopause, a chronic cough or heavy physical activity. The patient usually complains of urine loss on coughing or exertion which is called stress incontinence.
Bladder over-activity occurs when the bladder muscle contracts when it should be storing urine, leading to urgency and urge incontinence. This may be due to injury to the bladder's nerve supply or to a psychosomatic cause associated with anxiety. Occasionally both incompetenc of the sphincter and bladder over-activity co-exist.
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Incontinence is not a fatal condition but it can significantly interfere with professional, social, and personal activities with deterioration in the quality of life and sometimes social isolation. It is, therefore, important and worthwhile to have treatment.
Incontinence can be Cured
There are many different kinds of treatment depending on the cause. Firstly it is important to make sure that there isn't a urine infection (cystitis) as this can sometimes cause temporary incontinence and is easily treated.
If the main complaint is stress incontinence, pelvic floor excercises may be helpful. These have to be practised daily and a cure rate of up to 70% may be expected.
If these fail or are inappropriate, surgery is the next step. Conventional major surgery may achieve a success rate of 85% to 90% but there is usually a 4-6 day stay in hospital and some discomfort from the abdomial wound with an eventual return to work after 4 to 6 weeks.
An alternative approach is to inject bulking agents around the bladder neck (where the ureathra leaves the bladder) to prevent it opening too easily. This procedure may achieve up to 70% success but re-injection may be required.
TVT
A new technique has been devised which ovecomes the modest success rate of pelvic floor exercises and avoids the pain and long hospital stay of more major operations.
This procedure achieves between 85% to 90% success and has little post-perative pain so the patient leaves the hospital either on the same day or on the following day.
It works by supporting the middle of the urethra.
Gynecare TVT ia an exciting new concept. The mesh consists of a permanent Prolene material surrounded by a plastic sheath with a strong needle at either end. A small cut is made in the vagina and the mesh is passed under the middle of the urethra to support it. Both needles emerge through the anterior abdominal wall so that the mesh is accurately positioned.
A fine telescope (cystoscope) is introduced into the bladder to be absolutely sure there is no bladder injury, and then the position is adjusted and needles are removed.
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The vaginal and abdominal wounds are then closed and the patient returns to the ward. The operation takes up to 30 minutes. Some pain relief may be necessary and the patient usually passes urine within a few hours and can return home either the same day or the following day.
Published medical papers show that between 86% and 90% of patients are cured at a three year follow-up. (Ulmsten et al 1999; Olsson 1999).
Complications can include bleeding or bladder injury when the needles are passed, difficulty emptying the bladder, urgency and urinary infection. So far there have been no significant long-term side effects.
QUESTIONS & ANSWERS
- Am I a candidate for TVT?
If you complain of stress incontinence and urodynamic studies have shown that urethral sphincter incompetence is present, then thisoperation is likely to be suitable. It is appropriate for many types of patient, iincluding those who have had previous surgery for incontinence andare overweight. As with any surgery of this kind, the procedure should not be performed during pregnancy and the patient should be counselled that future pregnancies may negate the effects of the surgical procedure and she may again become incontinent.
- Will I have pain after the procedure?
Some mild pain may occur over twenty four to forty eight hours after surgery. This could be controlled by simple pain relief such as aspirin.
- Will I have difficulty emptying my bladder?
A few patients have temporary difficulty and may require an in-out catheter in the ward.
- What is the risk of urinary infection?
This may occur in up to 6% of patients and is treated by antibiotics and an adequate fluid intake.
- When can I play sport?
Usually after 4 to 8 weeks to allow the wounds to heal and the mesh to settle into place.
- When can I have intercourse?
After 4 to 6 weeks.
- Can I return to my usual routine?
Yes after about 1 -2 weeks, but it is wise to avoid unnecessary heavy lifting for 6 weeks.
- When can I drive?
Usually within 1 week of surgery.
- Does the mesh remain there forever?
Yes: evidence fom longterm follow-ups show that it is inert and remains ther to support the urethra.
- Are there any side effects from this?
Occasionally a portion of the mesh may be exposed but this is uncommon. It is treated by antibiotics, and closure of the wound.
- What happens if the mesh falls and I become incontinent again?
You would need to be investigated with fresh urodynamic tests and treatment decided on the basis of these. Occasionally a new Gynecare TT has to be inserted.
References
- Ulmsten U, Johnson P & Rezapour M. 1999. A 3 year follow up of tension free vaginal tape for surgical treatment of female stress urinary incontinence.
Brit. J. Obstet Gynaecol; 106:345-350.
- Olsson, Kroon 1999. A 3 year postoperative evaluation of tension free vaginal tape.
Gynecol. Ostet. Invest;48:267-269.
Last modified 13 January 2007 |
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